Opioid receptor blockade eliminates mood effects of aerobic gymnastics
by
Jarvekulg A, Viru A.
Institute of Exercise Biology,
University of Tartu, Estonia.
Int J Sports Med. 2002 Apr;23(3):155-7


ABSTRACT

The contribution of opioid receptors to the mood effects of aerobic gymnastics was tested by oral administration of naltrexone (25 or 50 mg) in 12 healthy women (aged 22 - 30 years). The opioid receptor blockade eliminated decreased anxiety, negative affect level and depressiveness as well as increased positive affect level, as found in a placebo trial after a 50 min session of aerobic gymnastics. 50 mg of naltrexone was more effective than 25 mg. Administration of 50 mg of naltrexone without exercise did not cause any significant changes in anxiety, positive and negative affect levels or depressiveness.
Mu
Pain
Heroin
SOD mu
Tolerance
Methadone
"Runners' high"
Naltrexone: suicide risk?
Naltrexone-induced dysphoria
Naltrexone (Trexan) : structure
Depression, opioids and the HPA
Kappa upregulation and addiction
Opioids, goldfish and the giant toad
Opioids, depression and learned helplessness
Stress, noradrenaline and endogenous opioids
"Runners' High" and endogenous opioid release


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